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Index > Protein center > Lalba(Gene name) > Mouse
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  • Lalba (Gene name),
  • Alpha-lactalbumin (Protein name ),  LALBA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Lalba;
    Protein name:
    Alpha-lactalbumin;
    Alternative:
    Lactose synthase B protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Lactose synthase (LS) is heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).
    Function:
    Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    143
    Sequence:
    50:
    MMHFVPLFLV | CILSLPAFQA | TELTKCKVSH | AIKDIDGYQG | ISLLEWACVL | 
    100:
    FHTSGYDTQA | VVNDNGSTEY | GLFQISDRFW | CKSSEFPESE | NICGISCDKL | 
    143:
    LDDELDDDIA | CAKKILAIKG | IDYWKAYKPM | CSEKLEQWRC | EKP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Alpha-lactalbumin
    Cat.:
    E1018h
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    96T
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    ELISA Kit for Mouse Alpha-lactalbumin
    Cat.:
    E1018b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Alpha-lactalbumin
    Cat.:
    E1018m
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    96T
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    ELISA Kit for Mouse Alpha-lactalbumin
    MSDS:
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    ELISA Kit for Mouse Alpha-lactalbumin
    Cat.:
    E1018p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Alpha-lactalbumin
    Cat.:
    E1018r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Alpha-lactalbumin
    Cat.:
    E1018d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Alpha-lactalbumin
    Cat.:
    U1018r
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Alpha-lactalbumin
    Cat.:
    U1018d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Alpha-lactalbumin
    Cat.:
    U1018m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Alpha-lactalbumin
    Cat.:
    U1018p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Alpha-lactalbumin
    Cat.:
    U1018b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Alpha-lactalbumin
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Alpha-lactalbumin
    Cat.:
    U1018h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Mouse Alpha-lactalbumin
    Polyclonal Antibody for Mouse Alpha-lactalbumin
    Cat.:
    P1018Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-lactalbumin
    Cat.:
    P1018Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-lactalbumin
    Polyclonal Antibody for Mouse Alpha-lactalbumin
    Polyclonal Antibody for Mouse Alpha-lactalbumin
    Polyclonal Antibody for Mouse Alpha-lactalbumin
    Cat.:
    P1018Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Alpha-lactalbumin
    Monoclonal Antibody for Mouse Alpha-lactalbumin
    Monoclonal Antibody for Mouse Alpha-lactalbumin
    Monoclonal Antibody for Mouse Alpha-lactalbumin
    Monoclonal Antibody for Mouse Alpha-lactalbumin
    Monoclonal Antibody for Mouse Alpha-lactalbumin
    Monoclonal Antibody for Mouse Alpha-lactalbumin
    Protein for Mouse Alpha-lactalbumin
    Protein for Mouse Alpha-lactalbumin
    Protein for Mouse Alpha-lactalbumin
    Protein for Mouse Alpha-lactalbumin
    Protein for Mouse Alpha-lactalbumin
    Protein for Mouse Alpha-lactalbumin
    Protein for Mouse Alpha-lactalbumin

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    Precision
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    Linearity
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    References
    1. 1.
      "Sequence of the murine alpha-lactalbumin-encoding cDNA: interspecies comparison of the coding frame and deduced pre-protein."
      Vilotte J.-L. , Soulier S. , Mercier J.-C.
      Gene112:251-255(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
    2. 2.
      "Isolation and characterization of the mouse alpha-lactalbumin-encoding gene: interspecies comparison, tissue- and stage-specific expression."
      Vilotte J.-L. , Soulier S.
      Gene119:287-292(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary gland.
    4. 4.
      "Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I."
      Ramakrishnan B. , Qasba P.K.
      J. Mol. Biol.310:205-218(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 21-143 IN COMPLEX WITH B4GALT1
    5. 5.
      "The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I."
      Ramasamy V. , Ramakrishnan B. , Boeggeman E. , Qasba P.K.
      J. Mol. Biol.331:1065-1076(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 21-143 IN COMPLEX WITH B4GALT1
    6. 6.
      "Alpha-lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc."
      Ramakrishnan B. , Shah P.S. , Qasba P.K.
      J. Biol. Chem.276:37665-37671(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.32 ANGSTROMS) OF 21-143 IN COMPLEX WITH B4GALT1 AND UDP-GLC
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